Hepatomegaly, Splenomegaly.? Hodgkin's Disease

Splenomegaly and hepatomegaly in an adolescent simulating Banti's syndrome.

Banti's disease, or Banti's syndrome as it is now generally called, is really a symptom complex, characterized by splenomegaly, and a progressive anaemia, with a tendency to gastro-oesophageal haemorrhage, and often accompanied by some degree of hepatic involvement. In Banti's description of the condition, he distinguished three stages:(1) Splenomegaly with an associated secondary anaemia. (2) ...

The Hodgkins Fund Prizes

Viral-related RNA in Hodgkins' disease and other human lymphomas.

Molecular hybridization with radioactively labeled DNA complementary to the RNA of the Rauscher leukemia virus was used to probe for homologous RNA in human lymphomas. 22 of 32 specimens contained RNA possessing homology to the RNA of the mouse leukemia virus, but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens. Normal adult and fetal tissues fa...

Motor neuron disease and its association with non-Hodgkins lymphoma.

M otor neuron disease (MND) is a neurodegenerative disorder characterized by muscle atrophy, brisk reflexes, spasticity, fasciculation, and atrophy. The onset of the disease is generally insidious. The pathological process may involve the motor cortex, the spinal cord, and the brainstem. 1 Only upper or only lower motor neurons may be affected. The disease may or may not be seen with neoplasms,...

Current strategies in the treatment of childhood Hodgkins disease.

Dramatic changes in the treatment of childhood Hodgkins disease have taken place during the past three decades. Contemporary combined modality treatment regimens produce durable disease-free survival in 90 to 100%of patients with early disease and in 70 to 85%of patients with advanced disease. Studies using chemotherapy alone also report high survival rates, and current studies are few to highl...